Re: Heart disease in an older hamster...
I had a male Syrian who died from suspected heart disease about a year ago, he was around 2 years 8 months when he passed.
Obvious signs are rapid breathing, lethargy, dizziness, and the hamster feeling cool to the touch. When the heart begins to malfunction it takes a lot out of a Syrian, but they can survive for remarkably long. I would say Hjalmar survived about 3 months after serious symptoms appeared. Watching him deteriorate was really tough, but right up until the end he was absolutely determined to continue as normally as possible.
In terms of medicine, there is not really anything you can do for the hamster at this point if she has heart failure. Just make it as easy as possible for her to get to her food, water, etc, and try to keep her warm.
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