Hello
I'm sorry to hear that your hamsters suffered health issues
I'm not too sure about this one as I have never had a female hamster. However, my previous male hamster, Toffee, died when he was about 1 1/2 years old. My current hamster, Sammy is 2 years old soon and going very, very strong. So really, Toffee died quite 'young' and he was male. We don't know the cause of his death.