Re: Is this a tumour?
I think this looks like Cushing's disease.
I think based on her quality of life and what your heart is telling you it would be a decision made from love to set her free. There is no cure for Cushings and it only gets worse. Once the skin is broken they can't fight off infections. She is already an elderly hamster too and has had a loved life.
I'm sorry she is going through this but I wouldn't put her through anymore treatments. She sounds like she is already uncomfortable. I hope her path is gentle and you can rest easy with any decision you make.
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