[cypher]

Unless it's a very small cage, too small, you wouldn't clean weekly anyway!
Other than spot cleaning pee you don't need to clean much at all, the nest area should always be left alone as much as possible unless it gets peed in, maybe clean some of it & replace it but never all once a month or so, same goes for the rest of the cage, you could do a partial clean about once a month, maybe a third with a cage the size of the detolf, scattering some of the old substrate back on top.
If you clean out the place where the hoard is then you can either just put it back or if it has fresh food mixed in then replace it with more hamster food.
Some people say to just clean the top layer but that will depend how much you ham digs & burrows, I find the substrate gets well mixed up with them digging & bit of food & poo tend to end up at the bottom of the cage.