I’ve successfully kept males and females in the same room. However, as souffle said, the two will generally try to get out and see one another when she goes into heat. With two males, they also did seem a slight more aggressive when it came to chewing on their cages. In the end though, as long as they have plenty of entertainment, and secure cages; I wouldn’t worry yourself over it too much, they get used to it. Best of luck with whatever you do choose