The size itself may work,but considering the wheel is not necessarily as solid as some it isn't the best idea.
There are some wheels which would look nice in a natural cage,for example the Silent Runner as it is a solid plastic wheel but it is extremely durable and the size will be a bit larger which means it could work for any size Syrian instead of just some
Unlike a wooden wheel,you also wouldn't need to put in any extra work to make it waterproof so it will last a very long time.You can get replacement parts if something stops working,so that makes it potentially the best wheel choice available.