Thanks everyone for your advice so far
The little lady arrived here today and seems constantly on edge, as soon as she hears anyone near the cage she charges out of her bed and sits on her shelf chattering her teeth, i've never known a hamster to do this before and i've had 18 myself! I guess somehow I need to calm her down before I even attempt to touch her but i'm not sure how when I don't understand why she's so on edge all the time.