Our instinct as humans is to clean everything at the same time and have everything just perfect, but with hamsters, it's best not to clean everything at the same time - eg do wheel one week, any toys another week etc and substrate a different week from other things.
Just had another look at your photo and I think adding a shoebox house or large-ish nesting box would help a lot and the bendy bridge you have could go over the door
That also makes a ramp up to the house roof. At the moment there is nowhere dark for her to retreat to. They also like to have a shelf or platform to sit under or climb onto (which is also a good place to put a food bowl - so would suggest putting a small platform at one end and the house at the other end with the wheel and toys in between.