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What species is she?
Some of the dwarf hams will always pee in the wheel whatever you do! With any ham the more you clean the more they pee as they can use it as a kind of scent marking especially when they are new & making their home their own.
What do you have in her toilet? Chincilla sand usually works best as they seem to like using that.
I would leave her to get on with it for now, don't be in a rush to clean anything too much but continue to put some wet substrate in the toilet tray & she may get the idea with time, if her house is big enough you could put it in there as it does tend to work best if you put the toilet in the same place as or as close as you can get to where they've chosen to pee.