It really depends on the hamster. Yes, females do go into heat every 4 days or so, but males have their own little odor!
I've only had one female and she was tiny, only about 112 grams! She was super active and always wanted to run around! She was super eager for o tame and was willing to climb up my arm on the day I brought her home! But, in the end, it really depends on the hamster!