hmm have you tried putting some veg oil around where the wheel spins? or if not get those silent wheels, thy are really good - i never hear my hammy on the wheel during the night and he always goes on it about 3/4am!
also if you mean she doesnt know how to use the wheel, maybe you should try and put her in it then give it a gentle sort of push to make it spin very gently so she knows what to do inside? i am taming my hammy right now and he is a realy sweetie!